Publications

• Oliveri AN, Knuth M, Glazer L, Bailey J, Kullman SW, Levin ED. Zebrafish show long-term behavioral impairments resulting from developmental vitamin D deficiency. Physiol Behav. 2020 Jun 17;224:113016. PMID: 32561170
• Oliveri AN, Glazer L, Mahapatra D, Kullman SW, Levin ED. Developmental exposure of zebrafish to vitamin D receptor acting drugs and environmental toxicants disrupts behavioral function. Neurotoxicol Teratol. 2020 May 27;81:106902. PMID: 32473203
• Stutts WL, Knuth MM, Ekelöf M, Mahapatra D, Kullman SW, Muddiman DC. Methods for Cryosectioning and Mass Spectrometry Imaging of Whole-Body Zebrafish. J Am Soc Mass Spectrom. 2020 Apr 1;31(4):768-772. PMID: 32129621
• Ideraabdullah FY, Belenchia AM, Rosenfeld CS, Kullman SW, Knuth M, Mahapatra D, Bereman M, Levin ED, Peterson CA. Maternal vitamin D deficiency and developmental origins of health and disease (DOHaD).J Endocrinol. 2019 Mar 1:JOE-18-0541.R2. PMID: 30909167
• Watson ATD, Nordberg RC, Loboa EG, Kullman SW. Evidence for Aryl hydrocarbon Receptor-Mediated Inhibition of Osteoblast Differentiation in Human Mesenchymal Stem Cells. Toxicol Sci. 2019 Jan 1;167(1):145-156. PMID: 30203000
• Grieshaber CA, Penland TN, Kwak TJ, Cope WG, Heise RJ, Law JM, Shea D, Aday DD, Rice JA, Kullman SW. Relation of contaminants to fish intersex in riverine sport fishes.
  Sci Total Environ. 2018 Dec 1;643:73-89. PMID: 29935363
• Mahapatra D, Franzosa JA, Roell K, Kuenemann MA, Houck KA, Reif DM, Fourches D, Kullman SW. Confirmation of high-throughput screening data and novel mechanistic insights into VDR-xenobiotic interactions by orthogonal assays. Sci Rep. 2018 Jun 11;8(1):8883. PMID: 29891985
• Lee B, Kullman SW, Yost EE, Worley-Davis L, Reckhow KH. An object-oriented Bayesian network approach for establishing swine manure-borne natural estrogenic compounds budget. Sci Total Environ. 2018 Oct 15;639:815-825. PMID: 29803052
• Lee B, Kullman SW, Yost EE, Meyer MT, Worley-Davis L, Michael Williams C, Reckhow KH. Corrigendum to “Predicting characteristics of rainfall driven estrogen runoff and transport from swine AFO spray fields” Sci. Total Environ. 532 (2015) 571-580. PMID: 30045565
• Benjamin Neelon SE, White AJ, Vidal AC, Schildkraut JM, Murtha AP, Murphy SK, Kullman SW, Hoyo C. Maternal vitamin D, DNA methylation at imprint regulatory regions and offspring weight at birth, 1 year and 3 years. Int J Obes (Lond). 2017 Jul 5. PMID: 28676681.
• Lee Pow CSD, Tilahun K, Creech K, Law JM, Cope WG, Kwak TJ, Rice JA, Aday DD, Kullman SW. Windows of Susceptibility and Consequences of Early Life Exposures to 17β-estradiol on Medaka (Oryzias latipes) Reproductive Success. Environ Sci Technol. 2017 May 2;51(9):5296-5305. PMID: 28379677.
• Lee Pow CS, Law JM, Kwak TJ, Cope WG, Rice JA, Kullman SW, Aday DD. Endocrine active contaminants in aquatic systems and intersex in common sport fishes. Environ Toxicol Chem. 2017 Apr;36(4):959-968. PMID: 27583571.
• Watson AT, Planchart A, Mattingly CJ, Winkler C, Reif DM, Kullman SW. From the Cover: Embryonic Exposure to TCDD Impacts Osteogenesis of the Axial Skeleton in Japanese medaka, Oryzias latipes. Toxicol Sci. 2017 Feb;155(2):485-496.  PMID: 28077779.
• Macaulay LJ, Chernick M, Chen A, Hinton DE, Bailey JM, Kullman SW, Levin ED, Stapleton HM. Exposure to a PBDE/OH-BDE mixture alters juvenile zebrafish (Danio rerio) development. Environ Toxicol Chem. 2017 Jan;36(1):36-48. PMID: 27329031..
• Lee Pow CS, Yost EE, Aday DD, Kullman SW. Sharing the Roles: An Assessment of Japanese Medaka Estrogen Receptors in Vitellogenin Induction. Environ Sci Technol. 2016 Aug 16;50(16):8886-95. doi: 10.1021/acs.est.6b01968. Epub 2016 Jul 26. PubMed PMID: 27391190.
• Kollitz EM, Zhang G, Hawkins MB, Whitfield GK, Reif DM, Kullman SW. Evolutionary and Functional Diversification of the Vitamin D Receptor-Lithocholic Acid Partnership. PLoS One. 2016 Dec 12;11(12):e0168278. doi: 10.1371/journal.pone.0168278.  PMID: 27942020.
• Planchart A, Mattingly CJ, Allen D, Ceger P, Casey W, Hinton D, Kanungo J, Kullman SW, Tal T, Bondesson M, Burgess SM, Sullivan C, Kim C, Behl M, Padilla S, Reif DM, Tanguay RL, Hamm J. Advancing toxicology research using in vivo high throughput toxicology with small fish models. ALTEX. 2016;33(4):435-452. doi: 10.14573/altex.1601281. PMID: 27328013.
• Lee B, Kullman SW, Yost EE, Meyer MT, Worley-Davis L, Williams CM, Reckhow KH. Predicting characteristics of rainfall driven estrogen runoff and transport from swine AFO spray fields. Sci Total Environ. 2015 Nov 1;532:571-80. PubMed PMID: 26102057.
• Sackett DK, Pow CL, Rubino MJ, Aday DD, Cope WG, Kullman SW, Rice JA, Kwak TJ, Law M. Sources of endocrine-disrupting compounds in North Carolina waterways: a geographic information systems approach. Environ Toxicol Chem. 2015 Feb;34(2):437-45. PMID: 25378272.
• Kollitz EM, Zhang G, Whitfield KG, Hawkins MB, Reif DM, Kullman SW. 2015. Molecular Cloning, Functional Characterization, and Evolutionary Analysis of Vitamin D Receptors Isolated from Basal Vertebrates. PLOS One. 10(4):e0122853
• Kullman SW. 2015. Conservation vs. Functional Diversification of Teleost NRs: Consequences for Contaminants of Emerging Concern. Response to ET&C Perspectives column. Environmental Toxicology and Chemistry.
• Sackett DK, Pow CL, Rubino M, Aday DD, Cope WG, Kullman SW, Rice JA, Kwak TJ, Law M. 2015. Sources of Endocrine disrupting Compounds in North Carolina Waterways; a GIS-Based Sampling Approach for Endocrine Disruption Studies. Environmental Toxicology and Chemistry. 34(2)437–445.
• Kollitz EM, Whitfied GK, Hawkins MB, Kullman SW. 2014.  Functional Diversification of Vitamin D Receptor Paralogs in Teleost Fish Following a Whole Genome Duplication Event. Endocrinology. 155(12):4641-54.
• Yost EE, Meyer MT, Dietz JE, Meissner B, Williams MC, Worley Davis L, Lee B, Kullman SW. 2014. Transport of Steroid Hormones, Phytoestrogens, and Estrogenic Activity Across a Swine Lagoon/Sprayfield System. Environmental Science and Technology. 48(19):11600-9.
• Lee B, Kullman SW, Yost EM, Meyer MT, Worley-Davis L, Williams CM, Reckhow KH. 2014. A Bayesian Network Model for Assessing Natural Estrogen Fate and Transport in a Swine Waste Lagoon. Integrated Environmental Assessment and Management. 10(4):511-21.
• Yost EE, Pow CL, Hawkins MB, Kullman SW. 2014. Bridging the Gap from Screening Assays to Estrogenic Effects in Fish: Potential Roles of Multiple Nuclear Estrogen Receptor Subtypes. Environmental Science and Technology. 48(9):5211-9.
• Van Wettere AJ, Law JM, Hinton DE, Kullman SW. 2014. Phenotypic Characterization of a Transgenic Japanese medaka (Oryzias latipes) Expressing a Red Fluorescent Protein in Hepatocytes. Toxicologic Pathology. 42(3):616-21.
• Yost EE, Meyer MT, Dietz JE, Meissner B, Williams MC, Worley Davis L, Lee B, Kullman SW. 2013. Comprehensive assessment of hormones, phytoestrogens, and estrogenic activity in an anaerobic swine waste lagoon.. Environmental Science and Technology. 47(23):13781-90.
• Van Wettere AJ, Kullman SW, Hinton DE, Law 2013. Immunohistochemical Characterization of the Hepatic Progenitor Cell Compartment in Medaka (Oryzias latipes) Following Hepatic Injury. Journal of Comparative Pathology. 149(4):434-45.
• Van Wettere AJ, Law JM, Hinton DE, Kullman SW. 2013. Anchoring Hepatic Gene Expression with Development of Fibrosis and Neoplasia in a Toxicant-Induced Fish Model of Liver Injury. Toxicologic Pathology. 41(5):744-60.
• Miller H, Clark B, Hinton DE, Whitehead A, Martin S, Kullman SW. 2012. Anchoring 17α-ethinylestradiol Induced Gene Expression Changes with Testicular Morphology and Reproductive Function in the Medaka Fish. PLOS One. 7(12):e52479.
• Dong W, Hinton DE, Kullman SW. 2012. TCDD Disrupts Hypural Skeletogenesis During Medaka Embryonic Development. Toxicological Sciences. 125(1):91-104.
• Law SHW, Redelings BD, Kullman SW. 2012. Comparative Genomics of Duplicate g-Glutamyl Transferase Genes in Teleosts: Medaka, Zebrafish, Takifugu, Tetraodon and Stickleback. Journal of Experimental Zoology Part B: Molecular and Developmental Evolution. 318(1):35-49.
• Krasowski MK, Ai N, Hagey L, Kollitz EM, Kullman SW, Reschly EJ, Ekins S,. 2011. The Evolution of Nuclear Hormone Receptor Activation by Bile Salts: Insights From the Green-Spotted Pufferfish (Tetraodon nigriviridis). BMC Biochemistry. 12:5.
• Dong W, Matsumura F, Kullman SW. 2010. TCDD Induced Pericardial Edema and Relative COX-2 Expression in Medaka (Oryzias latipes) Embryos. Toxicological Sciences. 118:213-23.
• Howarth DL, Hagey LR, Law SHW, Ai N, Krasowski MD, Ekins S, Moore JT, Hinton DE, Kullman SW. 2010. Two Farnesoid X Receptor Alpha Isoforms in Japanese Medaka (Oryzias Latipes) are Differentially Activated In Vitro. Aquatic Toxicology. 98:245-55.
• Howarth, DL, Law SHW, Law JM, Kullman SW, Hinton DE. 2009. Exposure to the Synthetic FXR Agonist GW4064 Causes Alterations in Gene Expression and Sublethal Hepatotoxicity in Larval Medaka (Oryzias latipes). Toxicology and Applied Pharmacology. 243(1):111-121.
• Hinton DE, Hardman RC, Kullman SW, Law JM, Schmale MC, Walter RB, Winn RN, Yoder JA. 2009. Aquatic Animal Models of Human Disease: Selected Papers and Recommendations from the 4th Conference. Comparative Biochemistry and Physiology C Toxicology Pharmacology. 149:121-8.
• Padilla S, Cowden J, Hinton DE, Yuen B, Law SHW, Kullman SW, Johnson R, Hardman C, Flynn K, Au, DWT. 2009. Use of Medaka in Toxicity Testing. Current Protocols in Toxicology. Supplement 39, Unit 1.10.
• Carney MW, Erwin K, Hardman RC, Yuen B, Volz DC, Hinton DE, Kullman SW. 2008. Differential Developmental Toxicity of Naphthoic Acid Isomers in Medaka (Oryzias latipes) Embryos. Marine Pollution Bulletin. 57:255-66.
• Howarth DL, Law S, Barnes B, Hall JM, Hinton DE, Moore L, Maglich JM, Moore JT, Kullman SW. 2008. Parologus VDRs in Teleosts: Transition of Nuclear Receptor Function. Endocrinology. 149:2411-22.
• Volz DC, Kullman SW, Howarth DL, Hardman RC, Hinton DE. 2008. Protective Response of the Ah Receptor to ANIT-Induced Biliary Epithelial Cell Toxicity in See-Through Medaka. Toxicological Sciences. 102:262-77.
• Hardman RC, Kullman SW, Yuen B, Hinton DE. 2008. Non Invasive High Resolution in Vivo Imaging of Hepatotoxicity in STII Medaka: Α-Napthylisothiocynate (ANIT) Induced Biliary Toxicity. Aquatic Toxicology. 86:20–37.
• Hardman RC, Kullman SW, Hinton DE. 2008. Non Invasive In Vivo Investigation of Hepatobiliary Structure and Function in STII Medaka (Oryzias latipes): Methodology and Applications. Comp Hepatol. 7:7.
• Hardman RC, Kullman SW, Hinton DE. 2007. Application of in Vivo Methodologies to Investigation Biological Structure, Function and Xenobiotic Response in See-Through Medaka (Oryzias latipes). The Fish Biology Journal, Medaka. 11:43-65.
• Linden KG, Rosenfeldt EJ, Kullman SW. 2007. UV/H₂O₂ Degradation of Endocrine-Disrupting Chemicals in Water Evaluated via Toxicity Assays. Water Science & Technology. 55:313–319.
• Hardman RC, Volz DC, Kullman SW, Hinton DE. 2007. An New In Vivo Look at Vertebrate Liver Architecture: 3 Dimensional Reconstructions from Medaka (Oryzias latipes). Anatomical Record. 290:770-82.
• Chen PJ, Kullman SW, Hinton DE, Linden KG. 2007. Comparisons of Low- and Medium- Pressure UV Lamps on the Removal of Bisphenol A Estrogenic Activity in Water Following Direct Photolysis and UV/H2O2 Oxidation Processes. Chemosphere. 68:1041-9.
• Kashiwada S, Kameshiro M, Shiraishi H, Arizono K, Kullman SW, Hinton DE. 2007. Estrogenic Modulation of CYP3A38, CYP3A40, and CYP19 in Mature Male Medaka (Oryzias latipes). Comparative Biochemistry and Physiology C Toxicology Pharmacology. 145:370-8.
• Rosenfeldt EJ, Chen PJ, Kullman SW, Linden KG. 2007. Destruction of Estrogenic Activity in Water Using UV Advanced Oxidation. Science of the Total Environment. 377:105-113.
• Chen PC, Rosenfeldt EJ, Kullman SW, Hinton DE, Linden KG. 2007. Biological Assessments of a Mixture of Endocrine Disruptors at Environmentally Relevant Concentrations in Natural River Water Following UV/H2O2 Oxidation. Science of the Total Environment. 376:18-26.
• Chen PJ, Linden KG, Rosenfeldt EJ, Kullman SW. 2006 Removal and Bio-Analytical Analysis of Endocrine Disrupting Compounds in Water With UV and UV/H2O2 Processes. Chemosphere. 65:1094-1102.
• Volz DC, Hinton DE, Law JM, Kullman SW. 2006. Dynamic Gene Expression Changes Precede Dioxin-Induced Liver Pathogenesis. Toxicological Sciences. 89:524-34.
• Kashiwada S, Hinton DE, Kullman SW. 2005. Functional Characterization of Medaka CYP3A38 and CYP3A40 by Expression in a Recombinant Baculovirus System. Comparative Biochemistry and Physiology C Toxicology Pharmacology. 141:338-348.
• Hinton DE, Kullman SW, Bencic DC, Hardman RC, Chen PJ, Carney M, Volz DC. 2005. Resolving Mechanisms of Toxicity While Pursuing Ecotoxicological Relevance. Marine Pollution Bulletin. 51:635-648 (Citation award).
• Volz DC, Bencic DC, Law JM, Hinton DE, Kullman SW. 2005. 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD) Induces Organ-Specific Differential Gene Expression in Japanese Medaka (Oryzias latipes). Toxicological Sciences. 85:572–584.
• Kullman SW, Kashiwada S, Hinton DE. 2004. Analysis of Medaka Cytochrome P4503A Homotropic and Heterotropic Cooperativity. Marine Environmental Research. 58:469-473.
• Liu Z, Kullman SW, Hinton DE, Torten M. 2003. ras Oncogene Mutations in Diethylnitrosamine-Induced Hepatic Tumors in Medaka. Mutation Research. 539:43-53.
• Kullman SW, Matsumura F, Hinton DE. 2003. Estrogen Signaling in Trout Liver: Activation of The Ras P21/MAP-Kinase Pathway. Environmental Science. 10:223-227.
• Kullman SW, Hinton DE. 2003. Analysis of Medaka CYP3A Gene Regulation, Promoter Regulatory Regions and Cloning of the Orphan Nuclear Receptor PXR. The MDIBL Bulletin. 42:29-31.
• Arukwe A, Kullman SW, Hinton DE. 2002. Molecular Cloning Characterization and Expression of the Eggshell Zona Radiata Gene in Nonylphenol and Estrogen-Treated Rainbow Trout (Oncorhynchus mykiss). Comparative Biochemistry and Physiology C Toxicology Pharmacology. 132:315-26.
• Kullman SW, Hinton DE. 2002. Toxicant Induced Differential Gene Expression and Production of an Aquatic Gene Array. The MDIBL Bulletin. 41:58-61.
• Arukwe A, Kullman SW, Hinton DE. 2001. Differential Biomarker Gene and Protein Expressions in Nonylphenol and Estradiol-17β Treated Juvenile Rainbow Trout (Oncorhynchus mykiss). Comparative Biochemistry and Physiology C Toxicology Pharmacology. 129:1-10.
• Kullman SW, Hinton DE. 2001. Identification of a Second Isoform of Cytochrome P450 3A from the Fresh Water Teleost Medaka (Oryzias latipes): Characterization and ontogeny. Molecular Reproduction Development. 58:149-158.
• Kullman SW, Hamm JT, Hinton DE. 2000. Identification and Characterization of a cDNA Encoding Cytochrome P450 3A from the Fresh Water Teleost Medaka (Oryzias latipes). Archives Biochemistry Biophysics. 380:29-38.
• Kullman SW, Matsumura F. 1997. Identification of a Novel Cytochrome P450 Gene from the White Rot Fungus (Phanerochaete chrysosporium). Applied Environmental Microbiology. 63:2741-2746.
• Kullman SW, Matsumura F. 1996. Metabolic Pathways Utilized by Phanerochaete chrysosporium for Degradation of the Cyclodiene Pesticide Endosulfan. Applied Environmental Microbiology. 62:593-600.
• Lucas AD, Bekheit HKM, Goodrow MH, Jones AD, Kullman SW, Matsumura F, Seiber JN, Hammock BD. 1993. Development of Antibodies Against Hydroxyatrazine and Hydroxysimazine: Application to Environmental Samples. Journal Agricultural Food Chemistry. 41:1523-1529.